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Urologic Pathology
Urologic Pathology Section supports clinical, educational, and academic activities in the area of genitourinary pathology.
Annually over 170 nephrectomies, >200 prostatectomies and >190 cystectomies are evaluated. Diverse kidney specimens include enucleation of small renal masses, partial nephrectomies as well as complex resections and cytoreductive nephrectomies. Most cystectomies are performed with extended lymph node dissections. Since 2014, MRI guided fusion prostate fusion biopsies have been performed.
Regular schedule of genitourinary tumor board meetings includes urologists, pathologists, radiologists, oncologists, and radiation therapy specialists.
Educational activities support the Pathology and Urology Residency programs as well as Fellowships in Surgical Pathology, Urologic Oncology, Endourology and Robotic Surgery, Male Pelvic Health, and Genitourinary reconstruction.
The Urologic Pathology Team:
Maria M. Picken MD, PhD, Director
Vijayalakshmi Ananthanarayanan MD
Selected publications:
Mutational Profile Using Next-Generation Sequencing May Aid in the Diagnosis and Treatment of Urachal Adenocarcinoma. Cornejo, K. M., et al. Int J Surg Pathol 2020; 28(1): 51-59.
Comparing oncologic outcomes in patients undergoing surgery for oncocytic neoplasms, conventional oncocytoma, and chromophobe renal cell carcinoma. Flack CK, Calaway AC, Miller BL, Picken MM et al. Urol Oncol. 2019; 37:811
Immunohistochemistry in the workup of bladder biopsies: Frequency, variation and utility of use at an academic center. McIntire, P., et al. (2019). Ann Diagn Pathol 41: 124-128.
Doshi, C. P., et al. (2019). "Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement." Case Rep Urol 2019: 8458706.
Challenges in Pathologic Staging of Renal Cell Carcinoma: A Study of Interobserver Variability Among Urologic Pathologists. Williamson SR, Rao P, Hes O, et al. (Picken MM). Am J Surg Pathol. 2018; 42:1253-1261
Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma. Ohe C, Smith SC, Sirohi D, Divatia M, et al. (Picken MM) Am J Surg Pathol. 2018; 42:279-292
Tumor enucleation specimens of small renal tumors more frequently have a positive surgical margin than partial nephrectomy specimens, but this is not associated with local tumor recurrence. Wang L, Hughes I, Snarskis C et al. (Picken MM) Virchows Arch. 2018;470:55-61